Skip to main content

Table 3 Adverse events during peptide vaccination

From: A phase II trial of personalized peptide vaccination in castration-resistant prostate cancer patients: prolongation of prostate-specific antigen doubling time

  Grade 1 Grade 2 Grade 3 Total
Injection site reaction 73 24 13 43
Constitutional symptoms     
  Bone pain 16 14 13 43
  Appetite loss 29 5 1 35
  Fatigue 23 11 0 34
  Edema peripheral 10 3 0 10
Blood/bone marrow     
  Lymphocytopenia 17 13 5 35
 Anemia 7 7 16 30
  White blood cell count decreased 6 6 5 17
Laboratory     
  Hypoalbuminemia 27 13 0 40
  ALP increased 20 8 6 34
  AST increased 24 4 1 29
  Hyponatremia 24 1 0 25
  ALT increased 13 2 1 16
  Blood triglycerides increased 10 2 0 12
  Creatinine increased 6 1 2 8