Table 3 Promoter methylation frequencies of SFRP2 , WIF-1 , DKK3 and SOX17 in relation with APC methylation
From: Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas
| Â | Nonpolypoid APC methylated | Nonpolypoid APC unmethylated | p-value | Polypoid APC methylated | Polypoid APC unmethylated | p-value | All adenomas APC methylated | All adenomas APC unmethylated | p-value |
|---|---|---|---|---|---|---|---|---|---|
SFRP2 | 91% (30/33) | 100% (7/7) | 1** | 93% (27/29) | 93% (14/15) | 1** | 92% (57/62) | 96% (21/22) | 1** |
WIF-1 | 59% (19/32) | 43% (3/7) | 0.7** | 93% (22/25) | 93% (12/14) | 1** | 71% (41/57) | 68% (15/21) | 1* |
DKK3 | 72% (23/32) | 86% (6/7) | 0.7** | 96% (24/25) | 100% (14/14) | 1** | 83% (47/57) | 96% (20/21) | 0.3** |
SOX17 | 91% (30/33) | 100% (7/7) | 1** | 100% (25/25) | 100% (14/14) | - | 95% (55/58) | 100% (21/21) | 0.6** |
All four combined | 37% (11/30) | 43% (3/7) | 1** | 80% (20/25) | 79% (11/14) | 1** | 56% (31/55) | 67% (14/21) | 0.4* |