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Table 4 Subgroup analysis according to preoperative treatment response

From: The influence of the treatment response on the impact of resection margin status after preoperative chemoradiotherapy in locally advanced rectal cancer

 

Good responders

 
 

CRM > 1.5 mm

CRM ≤ 1.5 mm

p†

Number of patients

63

10

 

5-year OS

93.3

90.0

.466

5-year DFS

87.6

90.0

.948

5-year LRC

94.9

100.0

.591

5-year DMFS

89.2

90.0

.817

 

Poor responders

 
 

CRM > 1.5 mm

CRM ≤ 1.5 mm

p†

Number of patients

56

22

 

5-year OS

87.4

48.4

<.001

5-year DFS

76.0

30.5

<.001

5-year LRC

85.7

58.0

<.001

5-year DMFS

78.2

33.0

<.001

  1. values are percentages unless indicated otherwise of patients; †log rank test. OS, overall survival; DFS, disease-free survival; LRC, locoregional control rates; DMFS, distant metastasis-free survival; CRM, circumferential resection margin.