Figure 2

Overall survival curves for each immunohistochemical staining group. a. The 5-year survival rate was significantly lower in the ZEB-1 positive group than in the ZEB-1 negative group (5-year 38.1 vs. 63.4%, p = 0.025). b. The 5-year survival rate was significantly higher in the preserved E-cadherin group than in the reduced E-cadherin group (5-year 66.0 vs. 45.5%, p = 0.048). c. When comparing between patients with ZEB-1 positive/ E-cadherin reduced and patients with other expression pattern combinations, ZEB-1(+)/E-cadherin(-) group showed a significantly poorer prognosis (5-year 29.5 vs. 62.2%, p = 0.005). d. There was no statistical difference in overall survival when E-cadherin expression was reduced in the ZEB-1 positive group (p = 0.24).