|
Factor
|
Number of patients
|
P value
|
HR
|
95.0% CI for HR
|
|---|
| | | | |
lower
|
upper
|
|---|
|
Site
| | | | | |
|
lower
|
450
| |
1
| | |
|
middle
|
89
|
0.85
|
1.04
|
0.73
|
1.47
|
|
upper
|
118
|
<0.01
|
1.47
|
1.12
|
1.94
|
|
entire
|
28
|
0.26
|
1.32
|
0.81
|
2.17
|
|
Borrmann type
| | | | | |
|
I/II
|
108
| |
1
| | |
|
III/IV
|
577
|
<0.01
|
1.60
|
1.16
|
2.21
|
|
Depth of invasion
| | | | | |
|
dMP
|
123
| |
1
| | |
|
SS
|
562
|
<0.01
|
1.57
|
1.16
|
2.13
|
|
Infiltrating pattern
| | | | | |
|
INF α/β
|
359
| |
1
| | |
|
INF γ
|
326
|
<0.01
|
1.41
|
1.14
|
1.75
|
|
TNM node stage
| | | | | |
|
N0 (0)
|
197
| |
1
| | |
|
N1 (1–2)
|
141
|
<0.01
|
3.01
|
1.17
|
5.31
|
|
N2 (3–6)
|
151
|
<0.01
|
3.32
|
1.97
|
5.59
|
|
N3a (7–15)
|
140
|
<0.01
|
5.54
|
3.38
|
9.09
|
|
N3b (>15)
|
56
|
<0.01
|
6.92
|
4.09
|
11.73
|
-
# Determined by multivariate Cox proportional hazards model.
