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Table 1 Adjusted odds ratios and 95% confidence intervals for lifestyle factors in 472 cases and 464 controls (recruitment period: December 2010 to November 2011)

From: Effects of lifestyle and single nucleotide polymorphisms on breast cancer risk: a case–control study in Japanese women

Variables

Case (n = 472)

Control (n = 464)

ORa(95% CIs)

 

n (%)

n (%)

  

Age (year) (mean ± SD)

54.72 ± 12.45

53.56 ± 11.00

  

Menopausal status

      

Pre

280

(59)

271

(58)

  

Post

192

(41)

193

(42)

  

Height (cm)

      

≤150

95

(20)

78

(17)

1.16

(0.78-1.71)

151-155

147

(32)

145

(32)

Ref.

 

156-160

152

(33)

156

(34)

0.99

(0.72-1.36)

>160

72

(15)

81

(18)

0.93

(0.63-1.38)

Weight (Kg)

      

≤50

159

(34)

173

(37)

0.97

(0.69-1.36)

51-55

112

(24)

118

(26)

Ref.

 

56 -60

92

(20)

78

(17)

1.24

(0.83-1.85)

>60

104

(22)

93

(20)

1.18

(0.80-1.73)

BMI (Kg/m2)

      

20

102

(22)

96

(21)

1.39

(0.96-2.01)

20-21.9

118

(25)

150

(33)

Ref.

 

22-23.9

104

(22)

102

(22)

1.28

(0.89-1.84)

≥24

139

(30)

112

(24)

1.54

(1.08-2.19)

Smoking status

      

Never

406

(87)

432

(94)

Ref.

 

Current or former

60

(13)

28

(6)

2.49

(1.56-4.06)

Alcohol drinking

      

Never

240

(51)

218

(47)

ref.

 

Current or former

231

(49)

243

(53)

0.91

(0.70-1.18)

Alcohol intake (g/day)

      

0

240

(51)

218

(48)

ref.

 

<5

140

(30)

130

(29)

1.02

(0.75-1.39)

5-10

53

(11)

62

(14)

0.82

(0.54-1.24)

10>

36

(8)

45

(10)

0.75

(0.46-1.21)

Meat intake (times/week)

      

≤1

101

(22)

66

(14)

Ref.

 

2-4

297

(64)

307

(67)

0.65

(0.45-0.92)

≥5

67

(14)

88

(19)

0.51

(0.32-0.80)

Soy intake (times/week)

      

≤1

45

(10)

49

(11)

Ref.

 

2-4

236

(50)

227

(50)

1.12

(0.72-1.76)

≥5

188

(40)

182

(40)

1.09

(0.69-1.72)

Fish intake (times/week)

      

≤1

103

(22)

94

(20)

Ref.

 

2-4

297

(64)

314

(68)

0.85

(0.62-1.18)

≥5

67

(14)

53

(11)

1.09

(0.68-1.74)

Eggs intake (times/week)

      

≤1

108

(23)

95

(21)

Ref.

 

2-4

238

(51)

247

(54)

0.86

(0.62-1.20)

≥5

120

(26)

112

(25)

0.96

(0.66-1.41)

Milk intake (times/week)

      

≤1

84

(18)

82

(18)

Ref.

 

2-4

157

(34)

135

(30)

1.14

(0.78-1.67)

≥5

226

(48)

238

(52)

0.92

(0.64-1.31)

Fruit intake (times/week)

      

≤1

112

(24)

112

(24)

Ref.

 

2-4

172

(37)

149

(32)

1.11

(0.79-1.57)

≥5

184

(39)

199

(43)

0.86

(0.61-1.21)

Mushrooms intake (times/week)

      

≤1

156

(34)

120

(26)

Ref.

 

2-4

247

(53)

261

(57)

0.73

(0.54-0.98)

≥5

61

(13)

77

(17)

0.60

(0.40-0.91)

Green and yellow vegetables intake (times/week)

      

≤1

47

(10)

28

(6)

Ref.

 

2-4

231

(50)

204

(46)

0.66

(0.39-1.09)

≥5

183

(40)

212

(48)

0.48

(0.29-0.80)

Coffee intake (times/week)

      

<1

132

(28)

103

(22)

Ref.

 

1

154

(33)

158

(34)

0.77

(0.55-1.09)

2-3

135

(29

160

(35)

0.68

(0.48-0.96)

≥4

45

(10)

40

(9)

0.91

(0.55-1.51)

Green tea intake (times/week)

      

<1

200

(43)

182

(40)

Ref.

 

1

151

(33)

133

(29)

0.97

(0.71-1.33)

2-3

63

(14)

87

(19)

0.63

(0.43-0.93)

≥4

48

(10)

55

(12)

0.72

(0.46-1.12)

Leisure-time exercise

      

None

254

(54)

214

(46)

Ref.

 

Current

214

(46)

248

(54)

0.70

(0.54-0.91)

Intensity of physical activityb (METs/week)

      

0

254

(56)

214

(47)

Ref.

 

>6.0

51

(11)

42

(9)

1.05

(0.67-1.65)

6.0-11.9

44

(10)

60

(13)

0.61

(0.39-0.93)

12.0-23.9

48

(11)

80

(17)

0.51

(0.34-0.75)

≥24.0

52

(12)

61

(13)

0.70

(0.46-1.07)

Age at menarche (year)

      

≤12

140

(30)

201

(44)

0.88

(0.616-1.25)

13

109

(23)

113

(25)

Ref.

 

≤14

217

(47)

144

(31)

1.25

(0.882-1.78)

Parity

      

0

86

(20)

75

(17)

Ref.

 

1-2

247

(57)

265

(59)

0.74

(0.511‒1.06)

≥3

102

(23)

107

(24)

0.76

(0.495‒1.15)

Age at first childbirth (year)

      

<25

151

(40)

142

(37)

1.22

(0.89-1.68)

25-29

162

(43)

187

(49)

Ref.

 

≥30

63

(17)

50

(13)

1.46

(0.96-2.25)

Breastfeeding

      

No

125

(27)

104

(23)

Ref.

 

Yes

339

(73)

355

(77)

0.77

(0.57-1.04)

History of benign breast disease

      

No

351

(79)

354

(79)

Ref.

 

Yes

93

(21)

92

(21)

1.03

(0.74-1.42)

Family history of breast cancer

      

No

391

(88)

373

(88)

Ref.

 

Yes

53

(12)

52

(12)

0.98

(0.65-1.47)

History of HRT use

      

No

424

(92)

412

(90)

Ref.

 

Yes

35

(8)

45

(10)

0.76

(0.47-1.21)

Education

      

High school or less

259

(55)

196

(43)

Ref.

 

Two-year college

144

(31)

144

(31)

0.78

(0.57-1.05)

University

64

(14)

120

(26)

0.41

(0.29-0.59)

  1. aOR is adjusted for age. bIntensity of physical activity in leisure-time exercise. Significant dates are showed in boldface. OR, odds ratio; CI, confidence interval; BMI, body mass index; HRT, hormone replacement therapy.