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Figure 4 | BMC Cancer

Figure 4

From: Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine

Figure 4

Time to progression (164 events) and overall survival (228 events) of patients according to RRM1 , RRM2B , and 2R status. (A) TTP according to RRM1 status. (B) OS according to RRM1 status. (C) TTP according to RRM2B status. (D) OS according to RRM2B status. (E) TTP according to RRM1 and RRM2B status combined. (F) OS according to RRM1 and RRM2B status combined. Abbreviations: 2R aberration, RRM1 and/or RRM2B aberrant; 2R normal, RRM1 and RRM2B both normal; CI, confidence interval; OS, overall survival; RRM1, ribonucleotide reductase M1 subunit; RRM2B, ribonucleotide reductase M2B subunit; TTP, time to progression.

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