|
Age (years)
|
71 (43–91)
|
74 (54–86)
|
72 (51–79)
|
0.05
|
|
Sex (male/female)
|
57/23
|
33/16
|
16/4
|
0.57
|
|
HBsAg positive (%)
|
8(10)
|
4 (8.2)
|
5 (25)
|
0.12
|
|
HCVAb positive (%)
|
52 (65)
|
24 (49)
|
7 (35)
|
0.03
|
|
AST (IU/l)
|
50 (18–148)
|
58 (14–240)
|
113 (13–384)
|
<0.0001
|
|
ALT (IU/l)
|
39 (10–202)
|
39 (12–190)
|
78 (8–157)
|
0.02
|
|
Total serum bilirubin (mg/dl)
|
0.7 (0.3-1.9)
|
1 (0.3-6.1)
|
1.6 (0.3-8.3)
|
<0.0001
|
|
Albumin (g/dl)
|
3.9 (3.5-5)
|
3.2 (2.1-4.6)
|
3.2 (2.2-3.4)
|
<0.0001
|
|
CRP (mg/dl)
|
0.1 (0.1-0.8)
|
0.3 (0.1-2.9)
|
2.6 (1.1-18.8)
|
<0.0001
|
|
WBC (cells/mm3)
|
5300 (2500–14800)
|
5100 (1800–14900)
|
5800 (3900–12400)
|
0.13
|
|
Platelet count (104/mm3)
|
14.2 (2.9-29.5)
|
11.6 (1.8-42.1)
|
17.3 (8.7-44.3)
|
0.07
|
|
Prothrombin time (%)
|
85 (38–100)
|
78 (41–100)
|
77 (45–97)
|
0.02
|
|
α-fetoprotein (ng/ml)
|
17 (1.9-59597)
|
52 (2–138011)
|
144 (1.7-280600)
|
0.01
|
|
Child-Pugh grade (A/B/C)
|
78/2/0
|
22/25/2
|
6/10/4
|
<0.0001
|
| CLIP score (0/1/2/3≧) |
35/31/10/4
|
8/12/17/12
|
0/7/1/12
|
<0.0001
|
| JIS score (0/1/2/3≧) |
17/32/27/4
|
0/15/17/17
|
0/1/6/13
|
<0.0001
|
|
BCLC score (0/A/B/C,D)
|
16/41/19/4
|
1/24/14/10
|
0/6/2/12
|
<0.0001
|
|
Tumor stage (І,ІІ,ІІІ,ІV)
|
16/34/28/2
|
4/22/16/7
|
1/4/4/11
|
<0.0001
|
|
Maximal tumor diameter (mm)
|
28 (7–90)
|
37 (10–200)
|
50 (10–130)
|
0
|
|
Tumor number (solitary/multiple)
|
45/35
|
26/23
|
5/15
|
0.04
|
|
Vascular invasion (absent/present)
|
77/3
|
44/5
|
13/7
|
0
|
|
Extrahepatic metastasis (absent/present)
|
79/1
|
47/2
|
17/3
|
0.02
|
