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Table 1 Clinicopahtological characteristics of patients grouped according to GPS

From: The Glasgow Prognostic Score, an inflammation based prognostic score, predicts survival in patients with hepatocellular carcinoma

Variable GPS 0 (n = 81) GPS 1 (n = 49) GPS 2 (n = 20) P-value
Age (years) 71 (43–91) 74 (54–86) 72 (51–79) 0.05
Sex (male/female) 57/23 33/16 16/4 0.57
HBsAg positive (%) 8(10) 4 (8.2) 5 (25) 0.12
HCVAb positive (%) 52 (65) 24 (49) 7 (35) 0.03
AST (IU/l) 50 (18–148) 58 (14–240) 113 (13–384) <0.0001
ALT (IU/l) 39 (10–202) 39 (12–190) 78 (8–157) 0.02
Total serum bilirubin (mg/dl) 0.7 (0.3-1.9) 1 (0.3-6.1) 1.6 (0.3-8.3) <0.0001
Albumin (g/dl) 3.9 (3.5-5) 3.2 (2.1-4.6) 3.2 (2.2-3.4) <0.0001
CRP (mg/dl) 0.1 (0.1-0.8) 0.3 (0.1-2.9) 2.6 (1.1-18.8) <0.0001
WBC (cells/mm3) 5300 (2500–14800) 5100 (1800–14900) 5800 (3900–12400) 0.13
Platelet count (104/mm3) 14.2 (2.9-29.5) 11.6 (1.8-42.1) 17.3 (8.7-44.3) 0.07
Prothrombin time (%) 85 (38–100) 78 (41–100) 77 (45–97) 0.02
α-fetoprotein (ng/ml) 17 (1.9-59597) 52 (2–138011) 144 (1.7-280600) 0.01
Child-Pugh grade (A/B/C) 78/2/0 22/25/2 6/10/4 <0.0001
CLIP score (0/1/2/3) 35/31/10/4 8/12/17/12 0/7/1/12 <0.0001
JIS score (0/1/2/3) 17/32/27/4 0/15/17/17 0/1/6/13 <0.0001
BCLC score (0/A/B/C,D) 16/41/19/4 1/24/14/10 0/6/2/12 <0.0001
Tumor stage (І,ІІ,ІІІ,ІV) 16/34/28/2 4/22/16/7 1/4/4/11 <0.0001
Maximal tumor diameter (mm) 28 (7–90) 37 (10–200) 50 (10–130) 0
Tumor number (solitary/multiple) 45/35 26/23 5/15 0.04
Vascular invasion (absent/present) 77/3 44/5 13/7 0
Extrahepatic metastasis (absent/present) 79/1 47/2 17/3 0.02
  1. Abbreviaions: HBsAg = hepatitis B surface antigen; HCVAb = hepatitis C antibody; AST = aspartate aminotransferase; ALT = alanine aminotransferase.
  2. CRP = C-reactive protein; WBC = white blood cell count; ICG = indocyanine green dye retention rate at 15 minutes; CLIP = Cancer of the Liver Italian Program.
  3. JIS = Japan Integrated Staging score; BCLC = Barcelona Clinic Liver Cancer; GPS = Glasgow Prognostic Score.