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Table 1 Baseline characteristics for patients with open-heart surgery in New Jersey between 1998–2004, by CPB status

From: Cardiopulmonary bypass has a modest association with cancer progression: a retrospective cohort study

 

All CABG patientsa(n=48,009)

Pumpb(n=35,795)

Off pump (n=12,214)

Length of hospital stay, mean (range)

11

(0–303)

10

(0–175)

Males, n (%)

 

25,868

(72.7)

8,547

(70.0)

Age, n (%)

<50

3,231

(9.0)

1,096

(9.0)

 

50-59

7,439

(20.8)

2,351

(19.3)

 

60-69

11,304

(31.6)

3,637

(29.8)

 

70-79

10,999

(30.7)

3,743

(30.7)

 

≥80

2,822

(7.9)

1,387

(11.4)

Race/ ethnicity, n (%)

White

30,030

(83.9)

9,744

(79.8)

 

Black

1,927

(5.4)

931

(7.6)

 

Hispanic

1,511

(4.2)

757

(6.2)

 

Other/unknown

2,327

(6.5)

782

(6.4)

Primary insurance, n (%)

Medicare/medicaid

16,254

(45.4)

6,450

(52.8)

 

Blue cross/commercial

6,021

(17.3)

2,070

(17.0)

 

HMO

7,801

(21.8)

2,351

(19.3)

 

Uninsured/indigent

924

(2.6)

366

(3.0)

 

Self pay

676

(1.9)

205

(1.7)

 

Other

3,939

(11.0)

772

(6.3)

Preoperative status c, n (%)

Elective

13,428

(37.5)

4,297

(35.2)

 

Urgent

20,369

(56.9)

7,412

(60.7)

 

Emergent

1,793

(5.0)

403

(3.3)

 

Salvage

78

(0.2)

13

(0.1)

Myocardial infarction, n (%)

15,934

(44.5)

5,073

(41.5)

Prior CV intervention, n (%)

8,987

(25.1)

2,823

(23.1)

Diabetes, n (%)

13,069

(36.5)

4,009

(32.8)

Hypertension, n (%)

27,153

(75.9)

8,779

(71.9)

Congestive heart failure, n (%)

5,981

(16.7)

2,034

(16.7)

Cardiogenic shock, n (%)

1,497

(4.2)

253

(2.1)

Endocarditis, n (%)

77

(0.2)

19

(0.2)

Cerebrovascular disease, n (%)

4,042

(11.3)

1,417

(11.6)

Smoke, ever, n (%)

18,724

(52.3)

6,454

(52.8)

Renal failure, n (%)

1,660

(4.6)

691

(5.7)

Lung disease, n (%)

Mild

3,427

(9.6)

1,078

(8.8)

 

Moderate

753

(2.1)

294

(2.4)

 

Severe

343

(1.0)

181

(1.5)

Peripheral vascular disease, n (%)

5,359

(15.0)

2,019

(16.5)

Disease vessels, n (%)

One

958

(2.7)

759

(6.2)

 

Two

5,721

(16.0)

2,010

(16.5)

 

Three

23,407

(65.4)

7,699

(63.0)

LM disease (>50% Occlusion), n (%)

10,055

(28.1)

3,208

(26.3)

Ejection fraction (%), n (%)

<20%

881

(2.5)

490

(4.0)

 

20-29%

2,494

(7.0)

725

(6.0)

 

30-39%

5,002

(14.0)

1,422

(11.7)

 

40-49%

8,703

(24.3)

2,641

(21.6)

 

≥50%

18,577

(51.9)

6,963

(56.8)

  1. aincludes patients with ≥1 isolated CABG surgeries; excludes patients with incidental valve surgery .
  2. bincludes patients with ≥1 on-pump procedure prior to incident cancer. Less than 0.2% of patients also had an off-pump procedure.
  3. celective: procedure deferred without increased risk of compromised cardiac outcome; urgent: not elective/emergent, required during same hospitalization to minimize chance of further clinical deterioration, worsening/sudden chest pain, congestive heart failure, acute myocardial infarction (AMI), anatomy, IABP, unstable angina with IV nitroglycerin or rest angina; emergent: ischemic dysfunction (ongoing ischemia including rest angina despite maximal medical therapy (medical and/or IABP), MI within 24 hours before surgery, or pulmonary edema requiring intubation), mechanical dysfunction (shock with or without circulatory support); emergent salvage: CPR enrout to the operating room or prior to anesthesia induction.
  4. Baseline characteristics were assessed at the time of the first open-heart surgery.
  5. %= n/N patients where n=frequency count in each category and N=total number of subjects.
  6. Due to rounding, sum of all percentages may equal 100%.
  7. CABG= coronary artery bypass graft, CPB=cardiopulmonary bypass (or “pump” procedure).
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BMC Cancer

ISSN: 1471-2407

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