SORBS2 and TLR3 induce premature senescence in primary human fibroblasts and keratinocytes

BMC Cancer

Table 3 Summary of the investigated genes and their influence on senescence in primary fibroblasts and keratinocytes (4 independent experiments each)

-no differences between expression of the gene and pCDH (empty vector).
+ / -≥ 2-fold number of senescent cells in comparison to the empty vector, but inconsistent between experiments.
+≥ 2-fold number of senescent cells in comparison to the empty vector.
++≥ 4-fold number of senescent cells in comparison to the empty vector.

ISSN: 1471-2407