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Figure 2 | BMC Cancer

Figure 2

From: Overexpression of heat shock transcription factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel

Figure 2

Fluorescent dyes efflux is enhanced in melanoma cells overexpressing HSF1. Intracellular fluorescence of doxorubicin (A) and eFluxx-ID™ Green Detection Reagent (B) in hHSF1-overexpressing cells is shown in relation to control (Neo) cells (C). The percentage of dye-negative cells (side population, SP) following incubation with Hoechst 33342 in the absence or presence of verapamil is presented. Mean values ± SD from at least three experiments are shown (asterisks indicate p < 0.05).

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BMC Cancer

ISSN: 1471-2407

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