Skip to main content

Table 2 Objective responses after TACE and correlation with tumor marker responses

From: Prognostic value of α-fetoprotein and des-γ-carboxy prothrombin responses in patients with hepatocellular carcinoma treated with transarterial chemoembolization

Radiologic response AFP response P value DCP response P value
  AFP responder AFP non-responder   DCP responder DCP non-responder  
  (n = 91, 79.1%) (n = 24, 20.9%)   (n = 77, 66.9%) (n = 38, 33.1%)  
WHO criteria 0.196   0.308
Complete response 0 (0) 0 (0) 0 (0) 0 (0)
Partial response 17 (18.7) 3 (12.5) 11 (14.3) 9 (23.7)
Stable disease 71 (78.0) 18 (75.0) 63 (81.8) 26 (68.4)
Progressive disease 3 (3.3) 3 (12.5) 3 (3.9) 3 (7.9)
mRECIST criteria
Complete response 70 (76.9) 13 (54.2) 0.045 55 (71.4) 28 (73.7) 0.298
Partial response 11 (12.1) 3 (12.5) 12 (15.6) 2 (5.3)
Stable disease 3 (3.3) 3 (12.5) 4 (5.2) 2 (5.3)
Progressive disease 7 (7.7) 5 (20.8)   6 (7.8) 6 (15.7)  
  1. Variables are expressed as n (%).
  2. AFP, alpha-fetoprotein; DCP, des gamma carboxy prothrombin; WHO, World health organization; mRECIST, modified Response Evaluation Criteria in Solid Tumor.