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Table 2 Objective responses after TACE and correlation with tumor marker responses

From: Prognostic value of α-fetoprotein and des-γ-carboxy prothrombin responses in patients with hepatocellular carcinoma treated with transarterial chemoembolization

Radiologic response

AFP response

P value

DCP response

P value

 

AFP responder

AFP non-responder

 

DCP responder

DCP non-responder

 
 

(n = 91, 79.1%)

(n = 24, 20.9%)

 

(n = 77, 66.9%)

(n = 38, 33.1%)

 

WHO criteria

0.196

 

0.308

Complete response

0 (0)

0 (0)

0 (0)

0 (0)

Partial response

17 (18.7)

3 (12.5)

11 (14.3)

9 (23.7)

Stable disease

71 (78.0)

18 (75.0)

63 (81.8)

26 (68.4)

Progressive disease

3 (3.3)

3 (12.5)

3 (3.9)

3 (7.9)

mRECIST criteria

Complete response

70 (76.9)

13 (54.2)

0.045

55 (71.4)

28 (73.7)

0.298

Partial response

11 (12.1)

3 (12.5)

12 (15.6)

2 (5.3)

Stable disease

3 (3.3)

3 (12.5)

4 (5.2)

2 (5.3)

Progressive disease

7 (7.7)

5 (20.8)

 

6 (7.8)

6 (15.7)

 
  1. Variables are expressed as n (%).
  2. AFP, alpha-fetoprotein; DCP, des gamma carboxy prothrombin; WHO, World health organization; mRECIST, modified Response Evaluation Criteria in Solid Tumor.