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Table 3 Relationship between expression of p-4E-BP1 and p-p70S6K and activation of ALK, AKT, and mTOR

From: Prognostic significance and therapeutic potential of the activation of anaplastic lymphoma kinase/protein kinase B/mammalian target of rapamycin signaling pathway in anaplastic large cell lymphoma

 

p-4E-BP1

p-value

p-p70S6K

p-value

+ (n = 64)

- (n = 7)

+ (n = 66)

- (n = 5)

ALK (n = 71)

      

 ALK+

40

4

 

42

2

 

 ALK-

24

3

0.783

24

3

0.119

p-AKT (n = 71)

      

 p-AKT+

50

4

 

51

3

 

 p-AKT-

14

3

0.244

15

2

0.408

p-mTOR (n = 71)

      

 p-mTOR+

56

1

 

55

2

 

 p-mTOR-

8

6

0.000*

11

3

0.038*

  1. *Statistically significant value.
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BMC Cancer

ISSN: 1471-2407

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