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Table 1 Combined effects of ACR and PI3K inhibitors on HLF cells

From: Synergistic growth inhibition by acyclic retinoid and phosphatidylinositol 3-kinase inhibitor in human hepatoma cells

 

LY294002 concentration

BKM120 concentration

ACR concentration

(μM)

(μM)

(μM)

5

10

15

5

10

15

0.5

+++

+

±

±

++

++

1

+++

++

±

+++

++

+

5

-

++

-

-

-

-

  1. Note:
  2. “-”, CI1.1-1.3 moderate antagonism;
  3. “±”, CI0.9-1.1 additive effect;
  4. “+”, CI0.8-0.9 slight synergism;
  5. “++”, CI0.6-0.8 moderate synergism;
  6. “+++”, CI0.4-0.6 synergism;
  7. Abbreviations: CI Combination index, ACR Acyclic retinoid.
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BMC Cancer

ISSN: 1471-2407

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