Figure 4From: RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients Phosphorylated RKIP in stage II colon cancer is associated with poor prognosis. (A) Representative examples of immunohistochemical staining for pRKIP showing strongly positive (3+) and negative levels. (B) Kaplan-Meier plot comparing the recurrence-free survival of patients with high versus low levels of nuclear pRKIP. Patients with lower levels experienced significantly longer recurrence-free survival (p = 0.0268). Bar is 100 micron. (C) Graphic representation of the correlation between lymphovascular invasion and pRKIP levels (p = 0.03).Back to article page