|
GENE
|
TP53 wt/mut p-value
|
ER pos/neg p-value
|
HER2 pos/neg p-value
|
|---|
| |
WT% meth
|
Mut% meth
|
p-value
| | |
|---|
|
BRCA1
|
87.34
|
79.99
|
0.001
| | |
|
PTEN
|
5.34
|
4.67
|
0.031
| |
3.6e-6
|
|
PPP2R2B
|
11.33
|
9.47
|
0.002
|
0.012
| |
|
FOXC1
|
17.12
|
13.56
|
0.017
|
0.032
| |
|
ABCB1
|
14.52
|
10.28
|
0.010
| | |
|
RASSF1A
|
32.48
|
26.58
|
0.028
|
0.004
|
0.023
|
|
GSTP1
| | | |
0.012
| |
|
CDKN2A
| | | | |
5.8e-9
|
|
MGMT
| | | | |
1.1e-7
|
|
ESR1
| | | | |
0.017
|
- Indicated are % methylation within the studied subgroups together with p-values for differences in DNA methylation levels between genes in connection with ER, HER2 and TP53 mutation status. Mann–Whitney test.
