Table 3 Toxicity according to National Cancer Institute common toxicity criteria version 3
Adverse event | All grades | Grade 3/4 | ||
|---|---|---|---|---|
(safety population n = 78) | ||||
pts (n) | % | pts (n) | % | |
Leucopenia | 2 | 2 | 0 | 0 |
Anemia | 4 | 5 | 1 | 1 |
Thrombocytopenia | 4 | 5 | 1 | 1 |
Infection | 29 | 37 | 6 | 7 |
Fatigue/Asthenia | 20 | 25 | 1 | 1 |
Diarrhea | 26 | 33 | 5 | 6 |
Mucositis | 14 | 18 | 1 | 1 |
Nausea | 22 | 28 | 4 | 5 |
Vomiting | 9 | 12 | 1 | 1 |
Anorexia | 8 | 10 | 1 | 1 |
Hand-foot-syndrome | 44 | 57 | 16 | 21 |
Gastrointestinal perforation | 2 | 2 | 2 | 2 |
Hemorrhage | 10 | 13 | 1 | 1 |
Hypertension | 17 | 22 | 3 | 4 |
Thromboembolic events | 12 | 15 | 8 | 10 |