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Table 4 One-way sensitivity analysis of important factors

From: Cost-effectiveness of adjuvant chemotherapy for curatively resected gastric cancer with S-1

Factor

Cost-effectiveness ratio ($/QALY gained)

Base case analysis

3,016

Simulation model

 

Log-normal

2,874

Weibull

3,341

Recurrence rate (95% CI: 30.5% - 38.8%)

2,446 ‒ 3,891

Utility

 

Remission after surgery (95% CI: 0.788 - 0.898)

2,825 ‒ 3,231

Metastasis (95% CI: 0.231 - 0.473)

2,998 ‒ 3,032

QALY gained (95% CI: 0.48 – 1.96)

1,901 ‒ 7,696

Recurrence cost (95% CI: $2,032 - $2,422)

2,834 ‒ 3,149

End of life cost (95% CI: $3,997 - $4,766)

2,682 ‒ 3,302

Exclusion of end-of-life costs due to gastric cancer

3,677

S-1 cost (95% CI: $4,322 - $4,772)

2,810 ‒ 3,173

Total cost difference (95% CI: $2,911 - $4,512 )

2,347 ‒ 3,638

  1. Discount rate: 3% for both cost and effectiveness, Period: lifetime.