Preoperative neutrophil/lymphocyte ratio predicts overall survival but does not predict recurrence or cancer-specific survival after curative resection of node-positive colorectal cancer

Table 2 Clinical and pathology characteristics of 322 patients with stage C colorectal cancer and association between these characteristics and NLR

	Total n = 322 n (%)	Median NLR	Mann- Whitney p value
Male	179 (55.6)	2.7	0.942
Female	143 (44.4)	2.6	0.942
Age ≥ 75 years	108 (33.5)	3.2	<0.001
Age < 75 years	214 (66.5)	2.5	<0.001
Rectal tumor	127 (39.4)	2.5	0.007
Colonic tumor	195 (60.6)	2.8	0.007
Tumour size ≥5cm	137 (42.5)	2.8	0.014
Tumour size <5cm	185 (57.5)	2.6	0.014
Mucinous or signet ring	34 (10.6)	2.9	0.433
Other adenocarcinoma	288 (89.4)	2.6	0.433
Direct spread beyond muscularis propria	271 (84.2)	2.7	0.718
Not beyond muscularis propria	51 (15.8)	2.5	0.718
Apical node involved	30 ( 9.3)	3.1	0.040
Not involved	292 (90.7)	2.6	0.040
≥ 4 nodes involved	102 (31.7)	2.8	0.467
< 4 nodes involved	220 (68.3)	2.7	0.467
≥ 40% of nodes involved	60 (18.6)	3.0	0.011
< 40% of nodes involved	262 (81.4)	2.6	0.011
Poorly differentiated	66 (20.5)	3.0	0.014
Moderately or well differentiated	256 (79.5)	2.6	0.014
Venous invasion	64 (19.9)	2.8	0.748
No venous invasion	258 (80.1)	2.7	0.748
Free serosal surface involved	76 (23.6)	3.1	0.010
Not involved	246 (76.4)	2.6	0.010
Adjacent structure infiltrated	23 ( 7.1)	3.7	0.021
Not infiltrated	299 (92.9)	2.6	0.021
Postoperative chemotherapy	197 (61.2)	2.5	0.006
No postoperative chemotherapy	125 (38.8)	3.0

ISSN: 1471-2407