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Table 2 Key clinical features of women with ovarian malignant tumors, ovarian benign tumors and healthy women (controls)

From: Symptoms, CA125 and HE4 for the preoperative prediction of ovarian malignancy in Brazilian women with ovarian masses

Characteristics

Malignant

Benign

Controls

p-value

p-value

p-value

(n = 60)

(n = 116)

(n = 150)

(Malignant vs. benign)

(Malignant vs. controls)

(Benign vs. controls)

Age

Years, mean (SD)*

50.8 (20.5)

47.9 (16.6)

44.4 (12.6)

0.45

0.02

0.18

Menopausal status Ŧ

Premenopausal

23 (38.3)

68 (57.8)

79 (52.6)

   

Postmenopausal

38 (61.7)

49 (42.2)

71 (48.4)

<0.01

0.05

0.37

Body mass index (BMI) – kg/m 2

Mean (+/− SD)*

28.3 (+/−6.3)

28.0 (+/−5.5)

27.2 (+/−5.0)

0.42

0.37

0.40

Histology

Epithelial

47 (78.3)

40 (34.5)

-

-

-

-

Invasive

37 (78.7)

     

Borderline

10 (21.3)

     

Germ line

6 (10.0)

28 (24.1)

-

-

-

-

Sex cord and Stromal

7 (12.7)

20 (17.3)

-

-

-

-

Non-neoplasic

-

28 (24.1)

-

-

-

-

Stage

I

32 (53.3)

     

II

5 (8.3)

     

III

22 (36.7)

     

IV

1 (1.7)

     
  1. p values calculated with either chi-squaresŦ or the Kruskal-Wallis test*.
  2. *2 ovarian carcinomas had endometrial carcinoma associated; for these cases ovarian carcinoma was considered the primary tumor.