|
Variables
|
Pioglitazone
|
|---|
|
Cases
|
Controls
|
Crude OR
|
†Adjusted OR
|
‡Adjusted OR
|
|---|
|
N = 357
|
%
|
N = 1,428
|
%
|
|---|
|
Nonuse
|
332
|
93.0
|
1,274
|
89.2
|
1.00
|
1.00
|
1.00
|
|
Any use
|
25
|
7.0
|
154
|
10.8
|
0.62*
|
0.65*
|
0.93
|
|
Recent use
|
11
|
3.1
|
75
|
5.3
|
0.56*
|
0.54
|
0.70
|
|
Past use
|
14
|
3.9
|
79
|
5.5
|
0.68*
|
0.77
|
1.28
|
|
Cumulative dosage
| |
|
< 260 DDDs
|
15
|
4.2
|
75
|
5.3
|
0.77
|
0.78
|
1.19
|
|
≥ 260 DDDs
|
10
|
2.8
|
79
|
5.5
|
0.49*
|
0.52
|
0.70
|
|
Cumulative duration
| |
|
< 1 year
|
17
|
4.8
|
89
|
6.2
|
0.73
|
0.74
|
1.14
|
|
≥ 1 year
|
8
|
2.2
|
65
|
4.6
|
0.47*
|
0.51
|
0.68
|
-
†: Multivariate model adjusted for age, sex, peptic ulcer history, ulcer bleeding history, Helicobacter pylori eradication rate, and comorbidities.
-
‡: Multivariate model adjusted for age, sex, peptic ulcer history, ulcer bleeding history, Helicobacter pylori eradication rate, comorbidities, and medications.
-
OR odds ratios, N number.
- *P < 0.05.
