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Table 3 Changes in estrogen receptor, progesterone receptor and her-2 oncogenes in SK-BR-3 cell and DMBA-induced tumors

From: Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice

 

DHA + CCM

Pvalue

CCM

P value

DHA

Pvalue

Gene expression (SK-BR-3 cells)

 

(n = 3)

(n = 3)

(n = 3)

PGR

1.67

0.628

2.05

0.294

1.16

0.991

ESR-1

2.90

0.00 1

1.04

0.994

1.19

0.581

ERBB2

0.97

0.119

1.01

0.187

1.08

0.227

Protein expression (DMBA-induced tumors)

 

(n = 4)

(n = 10)

(n = 10)

PR

0.38

0.913

0.67

0.962

0.80

0.992

ER-alpha

7.50

0.01

3.81

0.219

3.41

0.415

Her-2

2.60

0.261

1.68

0.704

0.97

1.00

  1. Values are fold changes compared to vehicle treated control. The data is analyzed by one-way ANOVA and Tukey’s post hoc test.