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Table 3 Changes in estrogen receptor, progesterone receptor and her-2 oncogenes in SK-BR-3 cell and DMBA-induced tumors

From: Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice

  DHA + CCM Pvalue CCM P value DHA Pvalue
Gene expression (SK-BR-3 cells)
  (n = 3) (n = 3) (n = 3)
PGR 1.67 0.628 2.05 0.294 1.16 0.991
ESR-1 2.90 0.00 1 1.04 0.994 1.19 0.581
ERBB2 0.97 0.119 1.01 0.187 1.08 0.227
Protein expression (DMBA-induced tumors)
  (n = 4) (n = 10) (n = 10)
PR 0.38 0.913 0.67 0.962 0.80 0.992
ER-alpha 7.50 0.01 3.81 0.219 3.41 0.415
Her-2 2.60 0.261 1.68 0.704 0.97 1.00
  1. Values are fold changes compared to vehicle treated control. The data is analyzed by one-way ANOVA and Tukey’s post hoc test.