Figure 5
From: Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer
CPE regulates p21, p27, and cyclin D1 expression. (A) Overexpression of CPE downregulated p21 and p27, and upregulated cyclin D1. Real-time qRT-PCR analysis of the relative expression of p21, p27, and cyclin D1 in the indicated cells. (B) Knockdown of CPE upregulated p21 and p27, and downregulated cyclin D1. Real-time qRT-PCR analysis of the relative expression of p21, p27, and cyclin D1 in the indicated cells. Data were normalized to GAPDH control and presented as mean ± SD from three independent experiments. *: P < 0.05.