Covariate | OS | TTP | OS from recurrence | Response at 3 months | Response at 6 months | Best response |
---|---|---|---|---|---|---|
(HR) [95% CI] | (HR) [95% CI] | (HR) [95% CI] | (OR) [95% CI] | (OR) [95% CI] | (OR) [95% CI] | |
EGFR | ||||||
Positive (n = 145) | 1.05 (0.77-1.43) | 0.82 (0.61-1.12) | 1.02 (0.75-1.41) | 0.64 (0.22-1.86) | 0.64 (0.46-4.15) | 1.06 (0.22-1.91) |
P = .75 | P = .21 | P = .89 | P = .41 | P = .96 | P = .43 | |
Negative (n = 54) | ||||||
Missing (n = 26) | ||||||
p53 | ||||||
Positive (n = 105) | 0.76 (0.55-1.05) | 0.92 (0.66-1.27) | 0.73 (0.52-1.03) | 3.01 (1.04-8.7) | 2.04 (0.68-6.1) | 2.64 (0.99-7.1) |
P = 0.10 | P = .60 | P = .071 | P = .043 | P = .21 | P = .053 | |
Negative (n = 97) | ||||||
Missing (n = 23) | ||||||
MGMT | ||||||
Positive (n = 65) | 0.97 (0.64-1.48) | 0.90 (0.59-1.36) | 1.42 (0.91-2.19) | 1.36 (0.35-5.34) | 1.02 (0.25-4.18) | 1.78 (0.52-6.13) |
P = 0.89 | P = 0.61 | P = .12 | P = 0.66 | P = .98 | P = .36 | |
Negative (n = 98) | ||||||
Missing (n = 62) |