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Table 3 Concordance between CNB and OEB for receptor status and Ki67 results

From: Preoperative core needle biopsy is accurate in determining molecular subtypes in invasive breast cancer

CNB OEB Concordance rate (%) Kappa P value
Negative Positive
ER    93.6 0.827 <0.001
  Negative 63 4    
  Positive 15 216    
PgR    85.9 0.704 <0.001
  Negative 95 25    
  Positive 17 161    
HER2    96.3 0.894 <0.001
  Negative 226 7    
  Positive 4 61    
Ki67 <14% ≥14% 79.5 0.545 <0.001
  <14% 70 42    
  ≥14% 19 167    
HR    93.6 0.824 <0.001
  Negative 61 5    
  Positive 14 218    
  1. Abbreviation: CNB, core needle biopsy; OEB, open excision biopsy; ER, estrogen receptor; PgR, progesterone receptor; HR, hormonal receptor.