Figure 1

Pygo2 expression analysis in lung cancer tissues. Pygo2 staining was classified as negative, weak (light staining; <70% nuclei stained), moderate (intermediate intensity staining; 80% nuclei stained), or strong (intense staining; >90% nuclei stained). Weak or negative Pygo2 staining was detected in the nuclei of normal bronchial epithelium (A, B). Weak (+) to strong (+++) nuclear accumulation of Pygo2 protein was observed in lung squamous cell carcinoma (C-H) and adenocarcinoma (I-N). Bar, 50 μm.