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Table 2 APOA1 rs670 A allele carriage was associated with lymph node and hormone receptor status at baseline

From: The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up study

  G/G (n=90) G/A (n=106) A/A (n=27) P valuea
Age 46.61±10.14 (29.25-74.55) 49.98±10.24 (29.87-74.57) 47.83±9.81 (29.25-67.91) 0.067
BMIb 23.47±4.14 (15.06-34.48) 23.03±4.16 (2.25-38.05) 23.77±3.83 (18.18-32.05) 0.654
Tumor type
Infiltrating ductal carcinoma 73 (81.11%) 97 (91.51%) 23 (85.19%) 0.332
Ductal carcinoma in situ 10 (11.11%) 5 (4.72%) 2 (7.41%)
Others 5 (5.56%) 4 (3.77%) 2 (7.41%)
Unknown 2 (2.22%) 0 (0.00%) 0 (0.00%)
Side
Right 35 (38.89%) 52 (49.06%) 13 (48.15%) 0.704
Left 51 (56.67%) 50 (47.17%) 13 (48.15%)
Bilateral 4 (4.44%) 4 (3.77%) 1 (3.70%)
Tumor size
<5cm 64 (71.11%) 76 (71.70%) 19 (70.37%) 0.227
≥5cm 6 (6.67%) 16 (15.09%) 4 (14.81%)
Unknown 20 (22.22%) 14 (13.21%) 4 (14.81%)
Lymph node involvement
Positive 22 (24.44%) 55 (51.89%) 13 (48.15%) 0.002
Negative 61 (67.78%) 46 (43.40%) 14 (51.85%)
Unknown 7 (7.78%) 5 (4.72%) 0 (0.00%)
TMN staging
Stages 0-2 63 (70.00%) 71 (66.98%) 20 (74.07%) 0.194
Stages >2 7 (7.78%) 19 (17.92%) 4 (14.81%)
Unknown 20 (22.22%) 16 (15.09%) 3 (11.11%)
ER/PR status
Single or double positive 63 (70.00%) 68 (64.15%)) 13 (48.15%) 0.006
Negative 13 (14.44%) 26 (24.53%) 13 (48.15%)
Unknown 14 (15.56%) 12 (11.32%) 1 (3.70%)
Family history
Positive 4 (4.44%) 3 (2.83%) (0.00%) 0.823
Negative 81 (90.00%) 97 (91.51%) 25 (92.59%)
Unknown 5 (5.56%) 6 (5.66%) 2 (7.41%)
  1. NOTE: Data shown represent number of patients (% of n) or mean±s.d.. Bold type indicates p<0.050.
  2. a, results of Chi-squared analysis or ANOVA test, depending on the type of parameter analyzed.
  3. b, results from 185 patients.
  4. Abbreviations: ER estrogen receptor, PR progesterone receptor.