Skip to main content

Table 2 APOA1 rs670 A allele carriage was associated with lymph node and hormone receptor status at baseline

From: The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up study

 

G/G (n=90)

G/A (n=106)

A/A (n=27)

P valuea

Age

46.61±10.14 (29.25-74.55)

49.98±10.24 (29.87-74.57)

47.83±9.81 (29.25-67.91)

0.067

BMIb

23.47±4.14 (15.06-34.48)

23.03±4.16 (2.25-38.05)

23.77±3.83 (18.18-32.05)

0.654

Tumor type

Infiltrating ductal carcinoma

73 (81.11%)

97 (91.51%)

23 (85.19%)

0.332

Ductal carcinoma in situ

10 (11.11%)

5 (4.72%)

2 (7.41%)

Others

5 (5.56%)

4 (3.77%)

2 (7.41%)

Unknown

2 (2.22%)

0 (0.00%)

0 (0.00%)

Side

Right

35 (38.89%)

52 (49.06%)

13 (48.15%)

0.704

Left

51 (56.67%)

50 (47.17%)

13 (48.15%)

Bilateral

4 (4.44%)

4 (3.77%)

1 (3.70%)

Tumor size

<5cm

64 (71.11%)

76 (71.70%)

19 (70.37%)

0.227

≥5cm

6 (6.67%)

16 (15.09%)

4 (14.81%)

Unknown

20 (22.22%)

14 (13.21%)

4 (14.81%)

Lymph node involvement

Positive

22 (24.44%)

55 (51.89%)

13 (48.15%)

0.002

Negative

61 (67.78%)

46 (43.40%)

14 (51.85%)

Unknown

7 (7.78%)

5 (4.72%)

0 (0.00%)

TMN staging

Stages 0-2

63 (70.00%)

71 (66.98%)

20 (74.07%)

0.194

Stages >2

7 (7.78%)

19 (17.92%)

4 (14.81%)

Unknown

20 (22.22%)

16 (15.09%)

3 (11.11%)

ER/PR status

Single or double positive

63 (70.00%)

68 (64.15%))

13 (48.15%)

0.006

Negative

13 (14.44%)

26 (24.53%)

13 (48.15%)

Unknown

14 (15.56%)

12 (11.32%)

1 (3.70%)

Family history

Positive

4 (4.44%)

3 (2.83%)

(0.00%)

0.823

Negative

81 (90.00%)

97 (91.51%)

25 (92.59%)

Unknown

5 (5.56%)

6 (5.66%)

2 (7.41%)

  1. NOTE: Data shown represent number of patients (% of n) or mean±s.d.. Bold type indicates p<0.050.
  2. a, results of Chi-squared analysis or ANOVA test, depending on the type of parameter analyzed.
  3. b, results from 185 patients.
  4. Abbreviations: ER estrogen receptor, PR progesterone receptor.