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Table 1 Summary statistics for clinical variables among the patient population

From: Interrogating differences in expression of targeted gene sets to predict breast cancer outcome

  

Mortality

Recurrence

Name

Mean (std dev) or N (%)

HR (95% CI)

P-value

Adj P-value

HR (95% CI)

P-value

Adj P-value

Age

59.8 (15.4)

0.99 (0.97, 1)

0.136

0.259

0.99 (0.97, 1)

0.161

0.307

Tumor size (mm)Ï®

29.6 (15.1)

1.01 (1, 1.03)

0.071

0.214

1.02 (1, 1.03)

0.026

0.077

NodesÏ®

       

Pos

134 (0.58)

1

-

-

1

-

-

Neg

97 (0.42)

1.78 (1.1, 2.88)

0.019

0.080

1.87 (1.17, 3.01)

0.010

0.036

Hormone therapy

       

No

162 (0.7)

1

-

-

1

-

-

Yes

71 (0.3)

0.89 (0.52, 1.51)

0.657

0.986

1.05 (0.63, 1.74)

0.847

1.000

Chemotherapy

       

No

152 (0.65)

1

-

-

1

-

-

Yes

81 (0.35)

2.14 (1.33, 3.45)

0.002

0.037

2.4 (1.5, 3.83)

<0.001

0.004

Radiation therapy

       

No

191 (0.82)

1

-

-

1

-

-

Yes

42 (0.18)

1.56 (0.89, 2.73)

0.121

0.259

2.1 (1.25, 3.53)

0.005

0.027

GradeÏ®

       

1 (well differentiated)

13 (0.06)

1

-

-

1

-

-

2 (intermediate)

86 (0.42)

2.37 (0.56, 9.94)

0.239

0.419

1.54 (0.47, 5.05)

0.479

0.839

3 or 4 (poorly differentiated or undifferentiated)

105 (0.51)

2.07 (0.49, 8.68)

0.319

0.516

1.42 (0.43, 4.63)

0.565

0.913

Disease stageÏ®

       

1

51 (0.22)

1

-

-

1

-

-

2

143 (0.62)

1.81 (0.85, 3.86)

0.126

0.259

2.05 (0.97, 4.36)

0.061

0.161

3

27 (0.12)

3.41 (1.39, 8.35)

0.007

0.039

3.69 (1.5, 9.03)

0.004

0.027

4

8 (0.03)

4.71 (1.54, 14.4)

0.007

0.039

3.21 (0.85, 12.1)

0.085

0.198

ER/PR

       

+/+

133 (0.57)

1

-

-

1

-

-

+/-

17 (0.07)

1.98 (0.82, 4.79)

0.128

0.259

3.68 (1.79, 7.58)

<0.001

0.004

-/+

30 (0.13)

2.1 (1.05, 4.21)

0.037

0.128

1.77 (0.86, 3.63)

0.118

0.249

-/-

53 (0.23)

2.26 (1.3, 3.94)

0.004

0.039

2.1 (1.19, 3.7)

0.010

0.036

  1. Univariate hazard ratios (HRs), 95% confidence intervals (CIs) and unadjusted/adjusted p-values for disease mortality and recurrence are included. N = number, std. dev. = standard deviation. ϮMissing values: Tumor size (6), Nodal status (2), Tumor grade (29), and Stage (4).