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Table 1 Baseline characteristics and Annexin A1 expression

From: Low Annexin A1 expression predicts benefit from induction chemotherapy in oral cancer patients with moderate or poor pathologic differentiation grade

Characteristics Total Annexin A1 expression P value*
patients Low High
N=256 N=96 N=136
n (%) n (%) n (%)
Gender
 Male 179 (69.9) 72 (77.2) 88 (61.0) 0.095
 Female 77 (30.1) 24 (22.8) 48 (39.0)  
Age (years)
 <60 168 (65.6) 67 (71.1) 90 (64.4) 0.562
 ≥60 88 (34.4) 29 (29.9) 46 (35.6)  
Site
 Tongue 113 (44.1) 42 (42.1) 56 (42.4) 0.281
 Buccal 45 (17.6) 15 (17.5) 28 (20.3)  
 Gingiva 40 (15.6) 11 (12.3) 27 (21.1)  
 Floor of mouth 30 (11.7) 16 (16.7) 13 (8.5)  
 Palate 18 (7.0) 7 (6.1) 7 (5.9)  
 Retromolar trigone 10 (3.9) 5 (6.1) 5 (2.5)  
Clinical T descriptor
 T1/T2 66 (25.8) 23 (24.6) 38 (28.0) 0.497
 T3/T4 190 (74.2) 73 (75.4) 98 (72.0)  
Clinical N descriptor
 N0 110 (43.0) 40 (39.5) 59 (45.8) 0.480
 N1 94 (36.7) 33 (39.5) 53 (34.7)  
 N2 52 (20.3) 23 (21.0) 24 (19.5)  
Clinical stage
 III 177 (69.1) 60 (65.8) 100 (72.0) 0.074
 IVA 79 (30.9) 36 (34.2) 36 (28.0)  
Pathologic differentiation
 Well 80 (31.2) 18 (22.8) 47 (33.1) 0.015
 Moderately 165 (64.5) 71 (71.1) 85 (63.6)  
 Poorly 11 (4.3) 7 (6.1) 4 (3.4)  
Smoking status**
 Current/former 126 (49.2) 52 (56.1) 58 (39.0) 0.084
 Never 130 (50.8) 44 (43.9) 78 (61.0)  
Alcohol use***
 Positive 98 (40.6) 44 (48.2) 44 (28.0) 0.037
 Negative 158 (59.4) 52 (51.8) 92 (72.0)  
  1. *P value from the chi-square test was reported to compare the difference between low and high Annexin A1 expression based on the different baseline factors.
  2. **Former/current smokers defined as at least a one pack-year history of smoking.
  3. ***Positive alcohol use was defined as current alcohol use of more than one drink per day for 1 year (12 ounces of beer with 5% alcohol, or 5 ounces of wine with 12%-15% alcohol, or one ounce of liquor with 45%-60% alcohol). All other patients were classified as negative alcohol use.