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Figure 2 | BMC Cancer

Figure 2

From: Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2

Figure 2

Immunoblot and immunohistochemical analysis of GnRH-I receptor (GnRH-IR) protein expression in endometrial cancer. (A) GnRH-I receptor levels in Ishikawa and ECC-1 cells were monitored by immunoblot assays. (B) GnRH-I receptor was stained brown in the second of three columns depicting human endometrial cancer tissue sections. Sections were counterstained with hematoxylin to show the nuclei in column 1 of three columns depicting human endometrial cancer tissue sections. Sections were stained without the GnRH-I receptor antibody as a negative control in the third of three columns depicting human endometrial cancer tissue sections. Micrographs were taken with a 40Χ objective lens. Scale bars represent 20 μm.

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BMC Cancer

ISSN: 1471-2407

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