The modified Glasgow prognostic score in prostate cancer: results from a retrospective clinical series of 744 patients

Table 4 Relative excess risk of death of prostate cancer patients based on Gleason score and PSA categories

	Modified Glasgow prognostic score			P-value for trend
	0	1	2
Gleason score-specific analysis
*Gleason < 7*
Relative excess risk (95% CI)^a	reference	1.66 (0.15-18.65)	46.04 (4.59-461.70)	0.013
Relative excess risk (95% CI)^b	reference	3.26 (0.67-15.89)	20.46 (3.43-121.97)	0.002
*Gleason = 7*
Relative excess risk (95% CI)^a	reference	3.06 (1.28-7.35)	2.19 (0.25-19.20)	0.021
Relative excess risk (95% CI)^b	reference	3.99 (1.78-8.97)	2.25 (0.31-16.08)	0.003
*Gleason 8-10*
Relative excess risk (95% CI)^a	reference	2.09 (1.29-3.37)	5.27 (2.73-10.22)	<0.001
Relative excess risk (95% CI)^b	reference	2.04 (1.30-3.22)	5.64 (3.00-10.59)	<0.001
*Unknown Gleason*
Relative excess risk (95% CI)^a	reference	1.55 (0.98-2.46)	2.18 (1.13-4.22)	0.015
Relative excess risk (95% CI)^b	reference	1.51 (0.96-2.37)	1.88 (0.98-3.61)	0.035
PSA-specific analysis
*PSA < 10ug/l*
Relative excess risk (95% CI)^a	reference	3.43 (1.37-8.59)	8.29 (2.76-24.87)	<0.001
Relative excess risk (95% CI)^b	reference	3.86 (1.48-10.03)	9.65 (3.13-29.75)	<0.001
*PSA 10-20ug/l*
Relative excess risk (95% CI)^a	reference	1.87 (0.63-5.58)	3.65 (0.47-28.49)	0.163
Relative excess risk (95% CI)^b	reference	2.54 (0.90-7.18)	2.50 (0.20-31.07)	0.088
*PSA > 20ug/l*
Relative excess risk (95% CI)^a	reference	2.20 (1.50-3.24)	5.08 (3.03-8.55)	<0.001
Relative excess risk (95% CI)^b	reference	2.25 (1.57-3.20)	5.01 (3.05-8.22)	<0.001

All estimates were presented after adjusted for age, deprivation and inpatient bed days. a = five-year relative survival, b = 10-year relative survival.

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