Table 3 Wee1 expression in relation to cell cycle proteins
From: High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients
Variables1 | Total | Nucleus | Cytoplasm | ||||
|---|---|---|---|---|---|---|---|
N | High | (%) | P 2 | High | (%) | P 2 | |
CDC25C cytoplasm | 0.9 | 0.015 | |||||
Low (≤ 3) | 110 | 29 | (26) | 48 | (44) | ||
High (> 3) | 187 | 48 | (26) | 109 | (58) | ||
Phospho-CDC25C (Ser216) cytoplasm | <0.001 | 0.18 | |||||
Low (≤ 3) | 147 | 23 | (16) | 72 | (49) | ||
High (>3) | 150 | 54 | (36) | 85 | (57) | ||
Phospho-CDC25C (Ser216) nucleus | 0.002 | 0.16 | |||||
Low (−) | 86 | 33 | (38) | 40 | (46) | ||
High (+) | 211 | 44 | (21) | 117 | (55) | ||
14-3-3β cytoplasm | 0.7 | 0.008 | |||||
Low (≤ 1) | 61 | 17 | (28) | 23 | (38) | ||
High (>1) | 236 | 60 | (25) | 134 | (57) | ||
14-3-3ϵ cytoplasm | 1.0 | 0.04 | |||||
Low (≤ 1) | 42 | 11 | (26) | 16 | (38) | ||
High (>1) | 255 | 66 | (26) | 141 | (55) | ||
14-3-3η cytoplasm | 0.07 | 0.003 | |||||
Low (≤ 3) | 138 | 29 | (21) | 60 | (43) | ||
High (>3) | 159 | 48 | (30) | 97 | (61) | ||
p21 nucleus3 | 0.04 | 0.5 | |||||
Low (−) | 119 | 21 | (18) | 62 | (52) | ||
High (+) | 88 | 26 | (30) | 50 | (57) | ||
Cyclin A nucleus3 | 0.004 | 0.2 | |||||
Low (< 5%) | 61 | 6 | (10) | 29 | (48) | ||
High (≥ 5%) | 146 | 41 | (28) | 83 | (57) | ||