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Table 2 Wee1 expression in relation to clinicopathological variables

From: High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients

Variables Total Nucleus Cytoplasm
  N High (%) P 1 High (%) P 1
Age     0.01    0.27
 25-69 117 41 (35)   68 (58)  
 70-84 146 27 (18)   74 (51)  
 85+ 34 9 (26)   15 (44)  
FIGO     0.40    0.12
 Ia 10 3 (30)   4 (40)  
 Ib 137 27 (20)   73 (53)  
 II 13 5 (38)   7 (54)  
 IIIa 64 22 (34)   27 (42)  
 IIIb 38 11 (29)   23 (60)  
 IIIc 12 2 (17)   10 (83)  
 IVa 5 1 (20)   1 (20)  
 IVb 13 4 (31)   8 (62)  
 Not available 5       
Lymph node metastasis     0.04    0.52
 None 164 36 (22)   87 (53)  
 Unilateral 89 32 (36)   44 (49)  
 Bilateral 38 8 (21)   23 (61)  
 Not available 6       
Tumor diameter (cm)     0.34    0.09
 0.3-2.5 88 17 (19)   39 (44)  
 2.6-4.0 93 25 (27)   56 (60)  
 4.1-20.0 100 28 (28)   55 (55)  
 Not available 16       
Tumor differentiation     0.10    0.007
 Well 73 12 (16)   27 (37)  
 Moderate 153 45 (29)   87 (57)  
 Poor 71 20 (28)   43 (61)  
Depth of invasion (mm)     0.79    0.16
 0.0-4.0 76 21 (27)   37 (49)  
 4.1-8.0 98 24 (24)   60 (61)  
 8.1-40.0 112 26 (23)   56 (50)  
 Not available 11       
Infiltration of vessel     0.18    0.67
 No 229 55 (24)   120 (52)  
 Yes 65 21 (32)   36 (55)  
 Not available 3       
  1. 1Pearson chi-square.
  2. High: Wee1 expression in nucleus ≥ 6 and in cytoplasm > 0.