Table 2 Wee1 expression in relation to clinicopathological variables
From: High expression of wee1 is associated with malignancy in vulvar squamous cell carcinoma patients
Variables | Total | Nucleus | Cytoplasm | ||||
|---|---|---|---|---|---|---|---|
N | High | (%) | P 1 | High | (%) | P 1 | |
Age | 0.01 | 0.27 | |||||
25-69 | 117 | 41 | (35) | 68 | (58) | ||
70-84 | 146 | 27 | (18) | 74 | (51) | ||
85+ | 34 | 9 | (26) | 15 | (44) | ||
FIGO | 0.40 | 0.12 | |||||
Ia | 10 | 3 | (30) | 4 | (40) | ||
Ib | 137 | 27 | (20) | 73 | (53) | ||
II | 13 | 5 | (38) | 7 | (54) | ||
IIIa | 64 | 22 | (34) | 27 | (42) | ||
IIIb | 38 | 11 | (29) | 23 | (60) | ||
IIIc | 12 | 2 | (17) | 10 | (83) | ||
IVa | 5 | 1 | (20) | 1 | (20) | ||
IVb | 13 | 4 | (31) | 8 | (62) | ||
Not available | 5 | ||||||
Lymph node metastasis | 0.04 | 0.52 | |||||
None | 164 | 36 | (22) | 87 | (53) | ||
Unilateral | 89 | 32 | (36) | 44 | (49) | ||
Bilateral | 38 | 8 | (21) | 23 | (61) | ||
Not available | 6 | ||||||
Tumor diameter (cm) | 0.34 | 0.09 | |||||
0.3-2.5 | 88 | 17 | (19) | 39 | (44) | ||
2.6-4.0 | 93 | 25 | (27) | 56 | (60) | ||
4.1-20.0 | 100 | 28 | (28) | 55 | (55) | ||
Not available | 16 | ||||||
Tumor differentiation | 0.10 | 0.007 | |||||
Well | 73 | 12 | (16) | 27 | (37) | ||
Moderate | 153 | 45 | (29) | 87 | (57) | ||
Poor | 71 | 20 | (28) | 43 | (61) | ||
Depth of invasion (mm) | 0.79 | 0.16 | |||||
0.0-4.0 | 76 | 21 | (27) | 37 | (49) | ||
4.1-8.0 | 98 | 24 | (24) | 60 | (61) | ||
8.1-40.0 | 112 | 26 | (23) | 56 | (50) | ||
Not available | 11 | ||||||
Infiltration of vessel | 0.18 | 0.67 | |||||
No | 229 | 55 | (24) | 120 | (52) | ||
Yes | 65 | 21 | (32) | 36 | (55) | ||
Not available | 3 | ||||||