Table 4 Shows percentage of rhabdoid tumor cell lines (A204, G401) surviving, in early or in late apoptosis after 72 h of treatment with SAHA as a single compound or in combination with 4HPR
Cell line | Control | SAHA 1 μM | SAHA 10 μM | 4HPR 1 μM | 4HPR 10 μM | SAHA 1 μM |
|---|---|---|---|---|---|---|
4HPR 1 μM | ||||||
A204 | ||||||
% surviving cells | 85.1 +/− 2.6 | 87.5 +/− 0.2 | 66.7 +/− 0.6 | 87.8 +/− 1.4 | 49.1 +/− 1.1 | 40.2 +/− 0.8 |
% early apoptosis | 4.8 +/− 0.1 | 4.1 +/− 0.2 | 8.5 +/− 0.2 | 6.2 +/− 1.0 | 7.7 +/− 0.5 | 6.9 +/− 0.4 |
% late apoptosis | 10.1 +/− 2.5 | 8.4 +/− 0.3 | 24.8 +/− 1.5 | 8.3 +/− 0.7 | 43.1 +/− 0.7 | 6.9 +/− 0.4 |
G401 | ||||||
% surviving cells | 90.3 +/− 0.8 | 91.2 +/− 1.5 | 64.7 +/− 2.9 | 92.3 +/− 2.2 | 60.0 +/− 2.2 | 62.9 +/− 3.2 |
% early apoptosis | 5.2 +/− 0.6 | 5.1 +/− 0.9 | 23.6 +/− 0.9 | 4.1 +/− 1.2 | 26.9 +/− 0.7 | 27.3 +/− 1.3 |
% late apoptosis | 4.5 +/− 0.2 | 3.8 +/− 0.7 | 11.7 +/− 2.1 | 3.6 +/− 1.0 | 13.1 +/− 1.4 | 9.8 +/− 4.2 |