Table 3 Multivariate logistic regression analysis of individual blood miRNA and miRNA classifier of miR-193a-3p, miR-23a and miR-338-5p

AUC

0.852

0.787

0.871

0.852

0.872

0.873

0.887

95% CI

0.768 - 0.935

0.685 - 0.889

0.800 - 0.942

0.770 - 0.935

0.798 - 0.946

0.803 - 0.942

0.821 - 0.953

Sensitivity (%)

100.0

94.3

81.4

74.3

94.3

81.4

80.0

Specificity (%)

56.2

53.1

75.0

81.2

65.6

75.0

84.4

Accuracy (%)

83.3

81.4

83.3

83.3

83.3

82.4

83.3

Youden’s Index^a

0.562

0.474

0.564

0.555

0.599

0.564

0.644

Cut-off value

0.346

0.502

0.640

0.745

0.474

0.636

0.728