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Table 1 Baseline patient and tumor characteristics

From: Clinical outcome, proteome kinetics and angiogenic factors in serum after thermoablation of colorectal liver metastases

Clinicopathological characteristics CSA RFA PH Unresectable p-value
n 20 22 134 29  
Median age (years) 66.7 60.0 62.3 60.8 0.151
  (IQR) (9.3) (16.7) (13.8) (17.4)  
Sex      0.392
  Female 10 (50%) 10 (45%) 55 (41%) 8 (28%)  
  Male 10 (50%) 12 (55%) 79 (59%) 21(72%)  
Site of primary tumor      0.732
  Colon 12 (60%) 15 (68%) 84 (63%) 21(72%)  
  Rectum 8 (40%) 7 (32%) 50 (37%) 8 (28%)  
Synchronous: metachronous liver metastasis 4:16 10:12 44:90 14:15 0.136
Interval resection of primary tumor and detection liver metastasis      0.385
  ≤12 months 9 (45%) 14 (64%) 88 (66%) 20 (69%)  
  >12 months 11(55%) 8 (36%) 46 (34%) 9 (31%)  
Node status of primary tumor      0.479
  Negative 8 (40%) 6 (27%) 50 (37%) 7 (24%)  
  Positive 12 (60%) 16 (63%) 84 (63%) 22 (76%)  
Adjuvant chemotherapy after primary      0.470
  No 12 (60%) 12 (55%) 92 (69%) 21 (72%)  
  Yes 8 (40%) 10 (45%) 42 (31%) 8 (28%)  
Size largest metastasis (cm)      
  Median (IQR) 4.0 (2.0) 3.0 (2.0) 5.0 (4.5) 3.5 (4.0)* 0.440
Number of liver metastases      <0.0001
  1 10 (50%) 6 (27%) 86 (64%) 6 (21%)  
  >1 10 (50%) 16 (63%) 48 (36%) 19 (66%) γ  
Preoperative CEA (μg/L)      
  Median (IQR) 21.2 (64.8) 12.0 (57.0) 22.5(71.4)$ 20.0 (116.3)& 0.623
CRS      0.009
  ≤2 15(75%) 10 (46%) 89 (66%)   
  >2 5 (25%) 12 (55%) 45 (34%)   
Surgical procedure      <0.0001
  No resection 13 (65%) 11 (50%) - 29 (100%)  
  < Hemihepatectomy 6 (30%) 7 (32%) 36 (27%)   
  Hemihepatectomy 1 (5%) 3 (14%) 56 (42%)   
  Extended - 1 (5%) 42 (31%)   
  Hemihepatectomy      
  1. *5 missing.
  2. γ 4 missing.
  3. $ 9 missing.
  4. & 2 missing.
  5. CSA, Cryosurgical ablation.
  6. RFA, Radiofrequency ablation.
  7. PH, Partial hepatectomy.
  8. CEA, Carcinoembryonic antigen.
  9. CRS, Clinical risk score.