Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma

BMC Cancer

Table 3 Summary of survival outcomes in T3-T4 nasopharyngeal carcinoma patients with a maximum primary tumor diameter (MPTD) ≤ 50 mm and MPTD > 50 mm

Variable	MPTD ≤ 50 mm	MPTD > 50 mm	Hazard ratio^†	Pvalue^‡
Variable	(N = 117)	(N = 113)	(95% CI*)	Pvalue^‡
5-yr OS rate	70.4%	58.4%	1.735 (1.130-2.664)	0.010
5-yr FFS rate	77.5%	65.2%	1.875 (1.131-3.107)	0.013
5-yr DMFS rate	83.6%	73.6%	1.811 (0.997-3.289)	0.047
5-yr LRFS rate	91.5%	87.9%	1.634 (0.688-3.882)	0.261

†Hazard ratios were calculated using the unadjusted Cox proportional-hazards model; *CI, confidence interval; ‡P values were calculated by the unadjusted log-rank test. OS, overall survival; FFS, failure-free survival; DMFS, distant metastasis-free survival; LRFS, local relapse-free survival; MPTD, maximum primary tumor diameter.

ISSN: 1471-2407