Skip to main content

Table 1 The genotypings of A133S in RASSF1A gene on ESCC and GCA patients and normal controls

From: Polymorphism of A133S and promoter hypermethylation in Ras association domain family 1A gene (RASSF1A) is associated with risk of esophageal and gastric cardia cancers in Chinese population from high incidence area in northern China

Genotypings*

Control

ESCC

GCA

n

(%)

n

(%)

P

OR

(95%CI)

n

(%)

P

OR

(95%CI)

Ala/Ala

211

(89.8)

99

(88.4)

   

94

(81.0)

   

Ala/Ser

23

(9.7)

11

(9.8)

0.96

1.02

(0.48–2.17)

18

(15.5)

0.09

1.76

(0.91–3.41)

Ser/Ser

1

(0.4)

2

(1.8)

0.24

4.26

(0.38–47.02)

4

(3.5)

0.04

9.01

(0.99–83.31)

Ala/Se and Ser/Ser

24

(10.2)

13

(11.6)

0.69

1.15

(0.51–2.44)

22

(19.0)

0.02

2.06

(1.09–3.97)

  1. *: Ala/Ala: homozygous for wild-type codon 133, Ala/Ser: heterozygote for codon 133, Ser/Ser: homozygous for codon A133S.