Table 2 Regions of amplification in unfavorable neuroblastoma (n=17)

chr:2:0.366-0.793

p25.3

0.427

1

TMEM18

NMA

1

chr:2:2.304-6.219

p25.3-p25.2

3.915

12

ADI1, ALLC, COLEC11, LOC150622, LOC400940, LOC730811, MYT1L, RNASEH1, RPS7, SOX11, TSSC1, TTC15

NMA

1

chr:2:3.605-4.280

p25.3

0.675

3

ALLC, COLEC11, RPS7

NMA

1

chr:2:5.708-7.439

p25.2-p25.1

1.731

6

CMPK2, LOC150622, LOC400940, RNF144A, RSAD2, SOX11

NMA

1

chr:2:6.372-6.855

p25.2

0.483

0

NMA

1

chr:2:10.413-11.244

p25.1

0.831

10

ATP6V1C2, C2orf50, HPCAL1, KCNF1, NOL10, ODC1 , PDIA6, PQLC3, ROCK2, SNORA80B

NMA

2

chr:2:11.622-11.878

p25.1

0.256

3

GREB1, LPIN1, NTSR2

NMA

1

chr:2:13.097-13.580

p24.3

0.483

0

NMA

1

chr:2:14.219-14.292

p24.3

0.073

0

NMA

2

chr:2:15.895-16.095

p24.3

0.200

2

MYCN , MYCNOS

NMA

16

chr:2:16.675-16.705

p24.3

0.030

1

FAM49A

NMA

6

chr:2:16.846-17.106

p24.3-p24.2

0.260

0

NMA

6

chr:2:18.197-18.423

p24.2

0.227

0

NMA

3

chr:2:20.546-21.012

p24.1

0.466

3

C2orf43, GDF7, HS1BP3

NMA

1

chr:2:22.493-25.674

p24.1-p23.3

3.181

21

ADCY3, ATAD2B, C2orf44, C2orf79, C2orf84, CENPO, DNAJC27, DNMT3A, DTNB, EFR3B, FKBP1B, ITSN2, KLHL29, LOC375190, MFSD2B, NCOA1, PFN4, POMC, SF3B14, TP53I3, UBXN2A

NMA

1

chr:2:26.853-27.169

p23.3

0.316

9

AGBL5, C2orf18, CENPA, DPYSL5, EMILIN1, KHK, LOC100128731, MAPRE3, TMEM214

NMA

2

chr:2:28.022-28.430

p23.2

0.408

1

BRE

NMA

2

chr:2:29.071-30.833

p23.2-p23.1

1.762

8

ALK , C2orf71, CAPN13, CLIP4, FAM179A, LBH, LCLAT1, YPEL5

NMA

2

chr:2:38.841-39.010

p22.1

0.168

4

DHX57, GEMIN6, LOC100271715, MORN2

NMA

1

chr:2:45.742-46.467

p21

0.725

2

EPAS1, PRKCE

NMA

1

chr:2:47.379-47.698

p21-p16.3

0.319

3

EPCAM, KCNK12, MSH2

NMA

1

chr:2:48.848-49.512

p16.3

0.664

1

FSHR

NMA

1

chr:3:170.768-172.093

q26.2

1.325

18

ARPM1, CLDN11, EIF5A2, GPR160, LOC100128164, LRRC31, LRRC34, LRRIQ4, MECOM, MYNN, PHC3, PRKCI , RPL22L1, SAMD7, SEC62, SKIL , SLC7A14, TERC

NMA

1

chr:3:173.047-173.459

q26.31

0.411

2

FNDC3B, TMEM212

NMA

1

chr:11:68.463-69.308

q13.2-q13.3

0.845

9

CCND1 , FGF19, FGF4 , IGHMBP2, MRGPRD, MRGPRF, MYEOV, ORAOV1, TPCN2

Not NMA, not 11q-

1

chr:12:56.182-57.066

q13.3-q14.1

0.884

23

AGAP2, AVIL, B4GALNT1, CDK4 , CTDSP2, CYP27B1, DCTN2, DDIT3, DTX3, FAM119B, GEFT, KIF5A, LOC100130776, MARCH9, MARS, MBD6, METTL1, OS9, PIP4K2C, SLC26A10, TSFM, TSPAN31, XRCC6BP1

Not NMA, not 11q-

1

chr:12:67.060-68.692

q15

1.632

13

BEST3, CCT2, CPM, CPSF6, FRS2, LRRC10, LYZ, MDM2 , NUP107, RAB3IP, RAP1B , SLC35E3, YEATS4

Not NMA, not 11q-

1

chr:12:71.578-73.413

q21.1

1.835

1

LOC552889

Not NMA, not 11q-

1

chr:12:83.287-83.563

q21.31

0.276

0

Not NMA, not 11q-

1

chr:12:116.476-116.802

q24.22-q24.23

0.326

1

KSR2

Not NMA, not 11q-

1