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Table 1 Main features of the 339 reported patients

From: Standard or hypofractionated radiotherapy in the postoperative treatment of breast cancer: a retrospective analysis of acute skin toxicity and dose inhomogeneities

 

Total patients (%)

CF Patients (%)

HS Patients (%)

P Value

No.

339

141 (41.59)

198 (58.41)

 

Mean age (range)

60 (22–86)

52 (22–79)

62.5 (38–86)

<0.001

Histology

   

NS

ILC

30 (8.8)

12 (8.5)

18 (9.1)

 

IDC

299 (88.2)

126 (89.4)

173 (87.4)

 

Intraductal

10 (3)

3 (21)

7 (3.5)

 

T stage

   

NS

T1

293 (86.4)

121 (85.8)

172 (86.7)

 

T2

46 (13.6)

20 (14.2)

26 (13.3)

 

N stage

   

NS

Nx

21 (6,3)

8 (5,7)

13 (6,5)

 

N0

251 (74)

93 (65.9)

158 (79.8)

 

N1

67 (19.7)

32 (22.6)

35 (17.6)

 

Grading (Bloom Richardson’s scale)

   

NS

G1

60 (17.7)

22 (15.6)

38 (19.2)

 

G2

131 (38.6)

58 (41.1)

73 (36.8)

 

G3

79 (23.3)

36 (25.5)

43 (21.7)

 

NA

69 (20.4)

25 (17.8)

44 (22.3)

 

Surgical margins

   

NS

Negative

295 (87)

124 (87.9)

171 (86.4)

 

Positive

5 (1.5)

2 (1.4)

3 (1.5)

 

Close (< 2 mm)

27 (8)

10 (7.1)

17 (8.6)

 

Tangents

12 (3.5)

5 (3.6)

7 (3.5)

 

Breast Volume

    

Average cc

718.7

684

725.4

NS

(range)

(188.6-2036.7)

(188.6-1899.9)

(193.3-2036.7)

Chemotherapy

    

Yes

126 (37.2)

68 (48.2%)

58 (29.3%)

 

No

211 (62.2%)

72 (51.1%)

139 (70.2%)

0.008

NA

2 (0.6%)

1 (0.7%)

1 (0.5%)

 

Hormone therapy

    

Yes

247 (72.8)

101 (71.6)

146 (73.7)

NS

No

74 (21.8)

34 (24.1)

40 (20,2)

 

NA

18 (5.4)

6 (4.3)

12 (6.1)

 

Trastuzumab

    

Yes

17 (5)

7 (5)

10 (5)

NS

No

327 (95)

134 (95)

188 (95)

 
  1. CF: Conventional Fractionation; HS: Hypofractionated Schedule; ILC: infiltrating lobular carcinoma; IDC: infiltrating ductal carcinoma; NA: not available; NS: not significant (P>0.05).