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Figure 4 | BMC Cancer

Figure 4

From: Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling

Figure 4

AKT suppression by ODAM is PTEN dependent. A) Western blot analysis of PTEN expression and AKT activation in whole cell lysates of C8161-CON and C8161-ODAM cells treated 72 hours with control or PTEN-specific siRNA as given in the methods. B) A375-ODAM and control cells were treated and analyzed for phospho-AKT and PTEN levels as in ‘A’.

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BMC Cancer

ISSN: 1471-2407

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