Variable | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
 | HR | 95% CI | P | HR | 95% CI | P |
Age | 1.03 | 0.46–2.59 | 0.95 |  |  |  |
Menopausal status | 0.89 | 0.42–2.04 | 0.77 |  |  |  |
Tumor size | 2.97 | 1.35–7.46 | 0.006 | 2.51 | 1.05–6.95 | 0.037 |
Nodal status | 2.07 | 1.02–4.31 | 0.044 | 1.81 | 0.86–3.96 | 0.12 |
Nuclear grade | 1.94 | 1.28–3.01 | 0.002 | 1.1 | 0.63–1.93 | 0.74 |
ER | 0.21 | 0.11–0.44 | <0.0001 | 0.29 | 0.12–0.72 | 0.0078 |
PgR | 0.32 | 0.15–0.65 | 0.0017 |  |  |  |
Her2 | 1.26 | 0.47–2.87 | 0.63 |  |  |  |
Ki67 Labeling Index | 2.3 | 0.96–6.82 | 0.063 |  |  |  |
Aurora A mRNA expression | 2.54 | 1.25–5.25 | 0.010 | 2.3 | 1.10–4.92 | 0.027 |
Aurora A amplification | 1.32 | 0.60–2.75 | 0.47 |  |  |  |
Aurora A protein expression | 1.45 | 0.65–3.01 | 0.35 |  |  |  |