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Figure 2 | BMC Cancer

Figure 2

From: Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis

Figure 2

Markers of cell proliferation and apoptosis in normal colonic mucosa and tumors from each treatment group. A. Representative Ki67-stained sections (magnification, 200×). Arrow indicates an adenoma. Arrowhead indicates an adenocarcinoma. Size bars represent 100 microns. B. Percentage of Ki67-positive cells in normal colon mucosa, adenomas and adenocarcinomas. C. Representative cleaved caspase 3-stained sections. Arrows indicate cleaved caspase 3-positive cells. D. Percentage of cleaved caspase-3-positive cells in normal colon mucosa, adenomas and adenocarcinomas. Bars in B and D represents mean ± SE. N = 8 and 7 for control and bethanechol-treated groups, respectively.

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