Figure 2From: Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis Markers of cell proliferation and apoptosis in normal colonic mucosa and tumors from each treatment group. A. Representative Ki67-stained sections (magnification, 200×). Arrow indicates an adenoma. Arrowhead indicates an adenocarcinoma. Size bars represent 100 microns. B. Percentage of Ki67-positive cells in normal colon mucosa, adenomas and adenocarcinomas. C. Representative cleaved caspase 3-stained sections. Arrows indicate cleaved caspase 3-positive cells. D. Percentage of cleaved caspase-3-positive cells in normal colon mucosa, adenomas and adenocarcinomas. Bars in B and D represents mean ± SE. N = 8 and 7 for control and bethanechol-treated groups, respectively.Back to article page