Table 3 Patients with dose-limiting toxicity events
huKS-IL2 dosing cohort, mg/m2 | Patient age, years | DLT | AE gradea | Day started (cycle) | Duration, days | DLT outcome |
|---|---|---|---|---|---|---|
2.0 | 63 | Hypoxia | 3 | 2 (1) | 2 | Recovered |
3.0 | 59 | Dyspnea | 3 | 3 (1) | 25 | Recovered |
Bronchospasm | 3 | 4 (1) | 2 | Recovered | ||
GGT increased | 3 | 4 (1) | 19 | Recovered | ||
4.0 | 55 | Thrombocytopenia | 4 | 8 (1) | 3 | Recovered |
Neutropenia | 3 | 8 (1) | 3 | Recovered | ||
63 | Anemiab | 3 | 5 (1) | 2 | Recovered |