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Figure 1 | BMC Cancer

Figure 1

From: Reduced mrna expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer

Figure 1

Relative CRHBP mRNA expression levels in renal tissues and comparison with clinicopathological parameters. A) Assorted difference plot for illustration of relative mRNA expression level differences between tumour and paired adjacent normal tissue samples of cc-RCCs. B) Groupwise bean plot comparison of relative CRHBP mRNA expression level in cc-RCC (TU) and normal kidney (aNT)shows approx. 33 fold reduction in CRHBP mRNA level (p<0.001). C) CRHBP mRNA level comparison in M+ and M- in cc-RCC indicates a significant reduction of CRHBP in metastasized state of the disease, p=0.026. D) CRHBP mRNA level comparison in advanced and localized disease demonstrates a higher expression of CRHBP in localized cc-RCC, p<0.001. E) CRHBP mRNA level comparison in high (T3) and low stage (T1) tumors (cc-RCC) shows a significant reduction of CRHBP in higher stages of disease, p=0.028.

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BMC Cancer

ISSN: 1471-2407

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