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Table 1 Association of panel score with clinicopathological parameters in the consecutive cohort

From: Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer

 

Panel score

 

0

1

2

3

p-value

Variables

(n = 9)

(n = 77)

(n = 105)

(n = 61)

 

Mean Age

    

0.765

≤50

1 (11.1)

11 (14.3)

15 (14.3)

12 (19.7)

 

>50

8 (88.9)

66 (85.7)

90 (85.7)

49 (80.3)

 

Tumour Size

    

0.475

≤2cm

6 (66.7)

54 (70.1)

66 (62.9)

35 (57.4)

 

>2cm

3 (33.3)

23 (29.9)

39 (37.1)

26 (42.6)

 

Histological type

    

0.378*

Indeterminate

0 (0.0)

8 (10.4)

5 (4.8)

7 (11.5)

 

Ductal

6 (66.7)

47 (61.0)

75 (71.4)

46 (75.4)

 

Lobular

2 (22.2)

14 (18.2)

12 (11.4)

4 (6.6)

 

Tubular

1 (11.1)

5 (6.5)

7 (6.7)

1 (1.6)

 

Medullary

0 (0.0)

0 (0.0)

4 (3.8)

2 (3.3)

 

Mucinous

0 (0.0)

3 (3.9)

2 (1.9)

1 (1.6)

 

Tumour Grade

    

<0.001*

I

4 (44.4)

25 (32.9)

23 (21.9)

4 (6.6)

 

II

5 (55.6)

42 (55.3)

38 (36.2)

19 (31.1)

 

III

0 (0.0)

9 (11.8)

44 (41.9)

38 (62.3)

 

Nodal status

    

0.029

N0

4 (66.6)

45 (68.2)

49 (51.0)

41 (73.2)

 

N1+

2 (33.3)

21 (31.8)

47 (49.0)

15 (26.8)

 

Unknown

3

11

9

5

 

ER status

    

0.006

ER Negative

0 (0.0)

4 (5.3)

21 (20.6)

14 (23.7)

 

ER Positive

8 (100)

72 (94.7)

81 (79.4)

45 (76.3)

 

Unknown

1

1

3

2

 

PR status

    

0.061

PR Negative

2 (28.6)

16 (26.2)

32 (37.2)

25 (51.0)

 

PR Positive

5 (71.4)

45 (73.8)

54 (62.8)

24 (49.0)

 

Unknown

2

16

19

12

 

Her2 status

    

0.036

0 - 2 +

6 (85.7)

69 (97.2)

88 (87.1)

48 (81.4)

 

3+

1 (14.3)

2 (2.8)

13 (12.9)

11 (18.6)

 

Unknown

2

6

4

2

 

Ki67 status

    

<0.001

0 - 10%

5 (62.5)

48 (62.3)

33 (32.7)

7 (11.7)

 

11 - 100%

3 (37.5)

29 (37.7)

68 (67.3)

53 (88.3)

 

Unknown

1

0

4

1

 
  1. *Linear-by-linear χ2 analysis; Others by Fisher’s Exact test.