Figure 4

The examination of the biological properties of SCC9 cells, stable SCC9 cells expressing an empty vector (SCC9-N) and MT1-MMP (SCC9-M). Overexpression of MT1-MMP in SCC9 cells resulted in a low adhesive, high invasive ability. (A) The quantification of cell adhesion rate at two time points. Each bar represents the mean ± s.d. **P<0.01. (B) Quantitative analysis of cell invasion in ten different random fields. The data were calculated as the mean ± s.d. **P<0.01. (C) Pictures presenting the cells penetrating the Matrigel basement membrane matrix after 24 h. Bar, 100 μm.