Ki67, TK1 and GLUT1 gene expression. At Day 10 after treatment start all tumors were excised and total RNA was isolated and revers transcribed to cDNA. Expression of Ki67, TK1 and GLUT1 were measured with qPCR and normalized to the geometric mean of two reference genes. Data are presents as fold changes in the treatment compared to the control group at Day 10. N = 5-7 tumors/group. *) p < 0.05, **) p < 0.01, ***) p < 0.001 treatment versus control group at same time point.