Figure 8
From: Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc −/+ ice
Immunofluorescent detection of apoptotic cells in intestinal adenoma. Representative analysis of tunnel staining in Apc −/+ control (A) and silibinin treated mice (B). Quantification of tunnel positive cells within the polyps (C) and within the crypts (D) in control (empty bar) and silibinin treated mice area (filled bar). (*p < 0.01 compared with control, by t test. n = 4 animals/group).