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Figure 1 | BMC Cancer

Figure 1

From: A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid malignancies

Figure 1

Chemical structures of Hsp90 inhibitors and ganetespib concentration vs. time curves. (A) Ganetespib (left) and 17-AAG, a prototypical geldanamycin-derived Hsp90 inhibitor (right); (B) Representative ganetespib concentration vs. time curves for a 216 mg/m2 dose. Red circles represent Day 1, blue squares represent Day 15.

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BMC Cancer

ISSN: 1471-2407

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